Trientine is a chelating (KEE-late-ing) agent. A chelating agent works by removing a heavy metal (such as lead, mercury, or copper) from the blood. Wilson's disease is a genetic metabolic defect that causes excess copper to build up in the body. Trientine is used to treat this inherited condition in people who cannot take penicillamine. Trientine may also be used for purposes not listed in this medication guide.
Syprine is a chelating agent belonging to a class of drugs known as antidotes. Chelating agents are capable of removing heavy metals in the body such as mercury, copper, and lead. Syprine is used in the treatment of Wilson's disease among patients who cannot be administered penicillamine. Syprine works by binding itself to copper to help in removing this metal from the blood.