Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Triamterene is a potassium-sparing diuretic that also prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. The combination of hydrochlorothiazide and triamterene is used to treat fluid retention (edema) and high blood pressure (hypertension). Hydrochlorothiazide and triamterene may also be used for purposes not listed in this medication guide.
Maxzide (triamterene/hydrochlorothiazide) is a potassium-sparing diuretic whose main function is to get rid of excess fluid in the body amid reducing potassium loss in the process. Potassium is an important mineral in the body and its levels must be maintained. Maxzide does this by blocking epithelial sodium channel on the collecting tubules of the kidneys. This in turn facilitates sodium excretion while reducing potassium loss. This drug is effective in the management of edema and hypertension.