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Timolol is a beta-blocker that also reduces pressure inside the eye. Timolol ophthalmic (for the eyes) is used to treat open-angle glaucoma and other causes of high pressure inside the eye. Timolol ophthalmic may also be used for other purposes not listed in this medication guide.Istalol is a drug that belongs to a class of medications known as beta-blockers. It is indicated for reducing pressure in the eye. It is used to treat high pressure of the eye or open-angle glaucoma. The drug works by lowering the amount fluid in the eye thus helping prevent blindness.