Zema is a steroid used to treat conditions such as disorders of the skin, blood, breathing. It is also used to treat ulcerative colitis, arthritis, lupus, and certain type of cancers. Zema is used prevent the release of substances in the body that cause inflammation by decreasing the effect of the body immune system. Zema is also used to reduce allergic reactions. Zema is available only with your doctor's prescription. Zema may weaken the overall immune system of your body.