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Voriconazole is an antifungal medication. Voriconazole is used to treat infections caused by yeast or other types of fungus. Voriconazole may also be used for purposes not listed in this medication guide.Voriconazole is a generic medication is marketed under the brand name Vfend. Voriconazole belongs to a class of drugs known as azole antifungals. Voriconazole is used in medicine for the treatment serious occurrence of an infection caused by fungus or yeast. Voriconazole mainly functions by creating an environment unsuitable for the growth and spread of fungus or yeast organisms.