Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung. Methotrexate is also used to treat severe psoriasis and rheumatoid arthritis. Methotrexate is usually given after other medications have been tried without successful treatment of symptoms. Methotrexate may also be used for purposes not listed in this medication guide.
Trexall is the brand of methotrexate sodium, which is a drug prescribed to treat psoriasis, neoplastic diseases, rheumatoid arthritis or diseases. It is classified as antimetabolite drug thus blocking the cells involved in metabolism. Metabolism involves production and destruction of essential components of the cells and the production of energy for use by the cell.