Tretinoin is a treatment meant for acne vulgaris. Treatment for any other disorder has not been evaluated yet. Its safety, as well as efficacy, has not been approved yet for the prevention or cure of any other disease. It has to be applied just once each day, before going to bed. It should be applied on the skin where the lesions can be seen. A thin layer has to be used in applying the affected regions. Tretinoin should be kept away from the mouth, eyes, mucous membranes and paranasal creases. Check out our Tretinoin discounts and coupons to start saving on your next prescription.