Treating HIV infection. It must be used in combination with other medicines. If Sustiva is taken alone to treat HIV, it may stop working. Sustiva is a nonnucleoside reverse transcriptase inhibitor (NNRTI). It works by blocking the growth of HIV.
Sustiva is a medicine used in the treatment of HIV, specifically the HIV type-1 variety. The active ingredient of the medicine is a drug called efavirenz. It works by inhibiting an enzyme called reverse transcriptase, an enzyme needed to transcribe viral RNA into DNA. Sustiva is usually taken in combination with other drugs, such as tenofovir and emtricitabine. Psychiatric side-effects are common with this drug.