Sirolimus lowers your body's immune system. The immune system helps your body fight infections. The immune system can also fight or "reject" a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader. Sirolimus is used to prevent your body from rejecting a transplanted kidney. Sirolimus is sometimes used in a combination treatment with cyclosporine (Neoral, Sandimmune) and a steroid medicine such as prednisone. Sirolimus may also be used for purposes not listed in this medication guide.
Sirolimus is one of the drugs used in preventing organ rejection after a transplant. Doctors advise that the drug should be used primarily on patients who have undergone a kidney transplant. The drug works by blocking a certain reaction in blood cells soon after a new organ is transplanted in a patient.
Sirolimus is an immunosuppressant that works by blocking the action of certain blood cells such as T lymphocytes, which causes the body to reject a transplanted organ. Sirolimus, when used with other drugs, prevents organ rejection after a kidney transplant. It can also treat a particular lung disease and prevent rejection of a heart transplant. Sirolimus can also treat psoriasis, but talk to your healthcare provider first about the possible risks of using this medication for your condition. This drug works by weakening your immune system to help your body accept your new organ. Do not stop taking Sirolimus without informing your pharmacist or doctor even if you feel well.