Treating moderate to severe rheumatoid arthritis (RA) in certain patients when used along with methotrexate. It is also used to treat psoriatic arthritis alone or with methotrexate. It may also be used to treat ankylosing spondylitis, moderate to severe ulcerative colitis, or for other conditions as determined by your doctor. Simponi is a TNF blocker. It works by blocking a protein (TNF-alpha) found in the body that causes inflammation.
Simponi (golimumab) is a prescription drug that is used for the treatment of rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and ulcerative colitis. Simponi contains a chemical ingredient, golimumab, which is a tumor necrosis factor (TNF) blocker. It helps in reducing the substance responsible for causing inflammation. Simponi is sometimes taken with another medicine called methotrexate.