Apremilast inhibits an enzyme within your immune system that can affect certain cells and contribute to inflammation in the body. Apremilast is used to treat the symptoms of active psoriatic arthritis in adults. Apremilast is also used to treat moderate to severe plaque psoriasis in people who may also receive phototherapy or other treatments for psoriasis. Apremilast can relieve tenderness and swelling in and around the joints, but this medicine is not a cure for psoriatic arthritis. Apremilast may also be used for purposes not listed in this medication guide.
Otezla is prescription medication approved for use in the treatment of certain skin conditions and arthritis. It is classified under phosphodiesterase inhibitors and is an anti-rheumatic drug. It works through inhibition by preventing inflammation.