The average Medroxyprogesterone cash price is about $15.01 for a supply of: Tablet 5 MG 30 pcs. Get our free Medroxyprogesterone coupon and be eligible to receive a discount. You can reduce your Medroxyprogesterone cost by up to 75% with our free Medroxyprogesterone discount card. Bring it to a participating pharmacy near you to save on your prescription medication.Medroxyprogesterone is a progestin (a form of progesterone), a female hormone that helps regulate ovulation (the release of an egg from an ovary) and menstrual periods. Medroxyprogesterone is used to treat conditions such as absent or irregular menstrual periods, or abnormal uterine bleeding. Medroxyprogesterone is also used to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens. Medroxyprogesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Medroxyprogesterone may also be used for purposes not listed in this medication guide.