Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation. Fluticasone nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies. Fluticasone nasal is for use in adults and children who are at least 2 years old. Fluticasone nasal may also be used for purposes not listed in this medication guide.