The average Flonase cash price is about $101.70 for a supply of: Suspension 50 MCG/ACT 16 Bottle. Get our free Flonase coupon and be eligible to receive a discount. You can reduce your Flonase cost by up to 75% with our free Flonase discount card. Bring it to a participating pharmacy near you to save on your prescription medication.Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation. Fluticasone nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies. Fluticasone nasal is for use in adults and children who are at least 2 years old. Fluticasone nasal may also be used for purposes not listed in this medication guide.