Bazedoxifene blocks estrogen from reaching certain cells in the uterine lining, to protect against overgrowth of uterine tissue. Estrogen is a female sex hormone produced by the ovaries. Conjugated estrogens are a mixture of estrogen hormones. Bazedoxifene and conjugated estrogens is a combination medicine used short-term in women after menopause to treat moderate to severe hot flashes, and to prevent osteoporosis. This medicine is used in women who have NOT had a hysterectomy (uterus removed). Conjugated estrogens should not be used to prevent heart disease, strokes, or dementia, because this medicine may actually increase your risk of developing these conditions. Bazedoxifene and conjugated estrogens may also be used for purposes not listed in this medication guide.
Duavee is a drug formulated using conjugated estrogens and bazedoxifene. It is used by women with a uterus to help reduce the intensity of symptoms associated with menopause such as vaginal dryness and hot flashes. It also prevents osteoporosis (bone loss) after menopause. The conjugated estrogens work by helping the body produce less estrogen, thereby dealing with menopausal symptoms while bazedoxifene acts like a selective estrogen receptor modular (SERM).
Duavee (bazedoxifene and conjugated estrogens) is a combination medication that is used in individuals who have reached their menopause stage. It treats various menopause symptoms such as vaginal dryness and hot flashes. It also believed to prevent osteoporosis (bone loss), a condition that is prevalent when a woman reaches menopause. Duavee works by the use of the two medicines forming it. Bazedoxifene blocks the estrogen hormone from reaching certain parts of the uterine lining and thus protecting uterine tissue against overgrowth. Conjugated estrogen increases the amount of estrogen to reduce the symptoms caused estrogen deficiency. Duavee is for short-term use in menopausal individuals and treats moderate to severe symptoms. Do not use this medicine if you have been diagnosed with stroke, blood clot or liver diseases.