Dolutegravir is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body. Dolutegravir is used with other antiviral medications to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Dolutegravir is not a cure for HIV or AIDS. This medicine is for use in adults and children who are at least 12 years old and weigh at least 88 pounds. Dolutegravir may also be used for purposes not listed in this medication guide.