Get our free Cortisone coupon and be eligible to receive a discount. You can reduce your Cortisone cost by up to 75% with our free Cortisone discount card. Bring it to a participating pharmacy near you to save on your prescription medication.Cortisone is a steroid that prevents the release of substances in the body that cause inflammation. Cortisone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Cortisone may also be used for purposes not listed in this medication guide.