Sucralfate is an anti-ulcer medication. Sucralfate is not greatly absorbed into the body through the digestive tract. It works mainly in the lining of the stomach by adhering to ulcer sites and protecting them from acids, enzymes, and bile salts. Sucralfate is used to treat an active duodenal ulcer. Sucralfate can heal an active ulcer, but it will not prevent future ulcers from occurring. Sucralfate may also be used for purposes not listed in this medication guide.
Carafate is a medication most commonly used to treat ulcers. Carafate is not absorbed by the body through the digestive tract, and mainly works by creating a lining in the stomach by binding to the tissue of ulcer sites and protecting them from acid, bile, salts and enzymes. Carafate is chemically combined with sucrose, sugar, sulfate and aluminum, and is classified as a protectant.