The average Acetaminophen cash price is about $2.99 for a supply of: Tablet 325 MG 30 pcs. Get our free Acetaminophen coupon and be eligible to receive a discount. You can reduce your Acetaminophen cost by up to 75% with our free Acetaminophen discount card. Bring it to a participating pharmacy near you to save on your prescription medication.There are many brands and forms of acetaminophen available and not all brands are listed on this leaflet. Acetaminophen is a pain reliever and a fever reducer. Acetaminophen is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. Acetaminophen may also be used for purposes not listed in this medication guide.