Accutane (isotretinoin) is an antineoplastic that is a form of Vitamin A. Accutane works by reducing the amount of oil glands in the skin of a patient. Accutane belongs to a class of drugs known as Retinoids. This drug helps renew the skin more quickly. Accutane is used to treat severe Cystic acne that is also known as nodular acne, which most of the time has not responded to other medication. The drug is mainly in the form of capsules that the patient has to swallow whole, and should not crush or chew. The dosage of Accutane is usually two capsules daily for 15 to 20 weeks.