The average Bayer aspirin cash price is about $8.81 for a supply of: Tablet 325 MG 30 pcs. Get our free Bayer aspirin coupon and be eligible to receive a discount. You can reduce your Bayer aspirin cost by up to 75% with our free Bayer aspirin discount card. Bring it to a participating pharmacy near you to save on your prescription medication.Treating minor aches and pains (eg, caused by headache, muscle aches, backache, arthritis, the common cold, toothache, menstrual cramps). It is used in certain patients to decrease the risk of stroke, heart attack, and death associated with stroke or heart attack. It may also be used for other conditions as determined by your doctor. Bayer is a salicylate. It works by inhibiting several different chemical processes within the body that cause pain, inflammation, and fever. It also reduces the tendency for blood to clot.