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Preventing and treating high levels of parathyroid hormone in certain patients with chronic kidney disease. Zemplar is a vitamin D compound. It works by blocking the formation and release of parathyroid hormone (PTH).Zemplar is used to treat and prevent secondary hyperparathyroidism (overactive parathyroid glands) in patients with chronic kidney disease. Hyperparathyroidism is a silent condition (causing no symptoms) caused when kidney function declines. Secondary hyperparathyroidism is very common in people in Stages 4 and 5 of chronic kidney disease and can cause the parathyroid glands to become permanently enlarged. Zemplar works by preventing the production of too much parathyroid hormone.
