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Fenofibric acid helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries). Fenofibric acid is used to treat high cholesterol and high triglyceride levels. It is sometimes given together with other cholesterol-lowering medications. Fenofibric acid may also be used for purposes not listed in this medication guide.Trilipix (fenofibric acid) belongs to the drug class called fibrates and is used to treat high cholesterol and high triglycerides. It works by increasing enzymes that help to break down fats like cholesterol and triglycerides, which can clog the arteries and cause atherosclerosis.