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Methylprednisolone is in a class of drugs called steroids. Methylprednisolone prevents the release of substances in the body that cause inflammation. Methylprednisolone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Methylprednisolone may also be used for other purposes not listed in this medication guide.Solu-Medrol generic name methylprednisolone belongs to a class of drugs known as Glucocorticoids. Solu-Medrol is used for treating certain conditions that are associated with the decreased adrenal gland functions in patients. Solu-Medrol is also used for treating severe inflammation that is caused by certain conditions that include severe asthma, allergies, rheumatoid arthritis. Solu-Medrol works by modifying the body's immune response to various conditions that will assist in decreasing inflammation.