Get our free Protriptyline hydrochloride coupon and be eligible to receive a discount. You can reduce your Protriptyline hydrochloride cost by up to 75% with our free Protriptyline hydrochloride discount card. Bring it to a participating pharmacy near you to save on your prescription medication.Treating depression. It may also be used for other conditions as determined by your doctor. Protriptyline is a tricyclic antidepressant. It works by increasing the activity of certain chemicals in the brain that help elevate mood.