Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body. Norgestimate is a form of progesterone, a female sex hormone important for the regulation of ovulation and menstruation. The combination of estradiol and norgestimate is used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. It is also used to prevent osteoporosis. Estradiol and norgestimate may also be used for purposes not listed in this medication guide.
Prefest is a combination of two products, estradiol and norgestimate. This medical combination is given to those women who exhibit symptoms of menopause like hot flashes and dryness. These conditions are brought forth when the body makes less estrogen than it had in the past. This medicine belongs to a group of drugs that are known as gonadotropins.