Get our free Oxymorphone hydrochloride coupon and be eligible to receive a discount. You can reduce your Oxymorphone hydrochloride cost by up to 75% with our free Oxymorphone hydrochloride discount card. Bring it to a participating pharmacy near you to save on your prescription medication.Treating moderate to severe pain. It may be used before surgery to cause sedation and reduce anxiety. It may also be used for other conditions as determined by your doctor. Oxymorphone is a narcotic pain reliever. It works in the brain and nervous system to reduce pain. It may also affect other body systems (eg, respiratory, circulatory) at higher doses.