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Glipizide is an oral diabetes medicine that helps control blood sugar levels. This medication helps your pancreas produce insulin. Glipizide is used together with diet and exercise to treat type 2 diabetes. Glipizide may also be used for other purposes not listed in this medication guide.Glucotrol XL is of the drug class Sulfonylureas. Its generic name is glipizide. Glucotrol XL checks the production of sugar in the liver and eases the diffusion of glucose in the tissues. Glucotrol eases the production of insulin in the body and thereby controlling the high blood pressure. Thus, the type II diabetes is controlled with Glucotrol XL. However, you cannot cure diabetes with Glucotrol XL.