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Alendronate is in the group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body. Alendronate slows bone loss while increasing bone mass, which may prevent bone fractures. Alendronate is used in men and women to treat or prevent osteoporosis that is caused by menopause or by taking steroids. Alendronate is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women. Alendronate may also be used for purposes not listed in this medication guide.Fosamax Plus D is a medication that comes in tablet form to increase the bone mass to treat osteoporosis. Osteoporosis is a condition that weakens the bones and causes them to break more frequently. Taking Fosamax Plus D can help stall or reverse the progress of osteoporosis.