Get our free Esomeprazole magnesium coupon and be eligible to receive a discount. You can reduce your Esomeprazole magnesium cost by up to 75% with our free Esomeprazole magnesium discount card. Bring it to a participating pharmacy near you to save on your prescription medication.Short-term treatment of gastroesophageal reflux disease (GERD) in patients with irritation and swelling of the esophagus when medicine cannot be taken by mouth. It is also used to reduce the risk of bleeding ulcers after a certain procedure (endoscopy). It may also be used for other conditions as determined by your doctor. Esomeprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced in the stomach.