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Treating certain conditions associated with decreased adrenal gland function. It is also used to treat severe inflammation due to certain conditions, including severe asthma, severe allergies, rheumatoid arthritis, ulcerative colitis, certain blood disorders, lupus, multiple sclerosis, and certain eye and skin conditions. It may also be used for other conditions as determined by your doctor. Dexamethasone is a corticosteroid. It works by decreasing or preventing tissues from responding to inflammation. It also modifies the body's response to certain immune stimulation.Desvenlafaxine is an antidepressant medication that is classified in a drug group referred to as selective serotonin and norepinephrine reuptake inhibitors (SNRIs). This drug mainly works on the central nervous system to enhance mood by increasing the concentration of two neurotransmitters known as norepinephrine and serotonin found in different sections of the brain. The full benefits of this drug may be achieved after several weeks of administration.