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Desvenlafaxine is an antidepressant medication that is classified in a drug group referred to as selective serotonin and norepinephrine reuptake inhibitors (SNRIs). This drug mainly works on the central nervous system to enhance mood by increasing the concentration of two neurotransmitters known as norepinephrine and serotonin found in different sections of the brain. The full benefits of this drug may be achieved after several weeks of administration.