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Misoprostol reduces stomach acid and replaces protective substances in the stomach that are inhibited by nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin. Misoprostol is used to prevent the formation of ulcers in the stomach during treatment with aspirin or an NSAID such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Aleve, Anaprox, Naprelan), oxaprozin (Daypro), indomethacin (Indocin), diclofenac (Voltaren, Cataflam), etodolac (Lodine), piroxicam (Feldene), meloxicam (Mobic), tolmetin (Tolectin), nabumetone (Relafen), and fenoprofen (Nalfon). NSAIDs and aspirin are used to treat pain, fever, arthritis, and inflammatory conditions. Misoprostol may also be used for purposes other than those listed in this medication guide.Cytotec (Misoprostol) is a drug belonging to the Prostaglandin class of drugs. It is used to inhibit stomach ulcers brought about by the use of anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen or aspirin. Cytotec works by lowering the amount of acid released by the stomach. It shields the stomach's lining, thereby reducing the risk of stomach ulcers.
