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What is akynzeo? Akynzeo is a brand name for a generic drug known as netupitant/palonosetron. It is used to prevent nausea and vomiting that are commonly associated with chemotherapy. It is marketed by Helsinn Therapeutics. Let's discuss akynzeo and what it is used for. What is the best way to use it?
The recommended dosage of Akynzeo is one capsule per day, one hour before the first day of chemotherapy. You should swallow the capsule whole and drink water afterward. Akynzeo is not recommended to be taken on the days following chemotherapy. It can be taken with or without food, and is taken as directed by your doctor. For best results, you should only take this drug on days you will be receiving chemotherapy.
If you take too much Akynzeo, contact your doctor or local Poison Control Center immediately. If you take other medications, such as SNRIs (serotonin-norepinephrine reuptake inhibitors), it may affect Akynzeo. The amount you take may depend on your individual needs and medical history. If you have any allergies to any drugs, tell your doctor.
When you take Akynzeo, you will have to take dexamethasone in addition to the medicine. Dexamethasone prevents nausea caused by chemotherapy. Akynzeo blocks serotonin receptors in the central nervous system. Netupitant, a separate drug, inhibits the activity of substance P/neurokinin 1 receptors and prevents vomiting during the acute phase of chemotherapy.
Side effects of Akynzeo include dizziness, somnolence, and fatigue. If you experience any of these, you should not drive or operate machinery. You should also consult your doctor if these symptoms become bothersome. Akynzeo is usually prescribed to prevent nausea and vomiting associated with cancer chemotherapy. However, the side effects can be serious. As with any drug, you should always report them to your doctor.
AKYNZEO may increase plasma levels of erythromycin, midazolam, alprazolam, triazolam, and benzodiazepines. It may also reduce the efficacy of rifampicin. If you're interested in purchasing this drug, you should ask your healthcare provider about it. This generic drug is available and can be an excellent alternative to the original drug.
AKYNZEO capsules have a half-life of 44 hours and a systemic clearance of 5.5 L/h in healthy subjects. The corresponding AKYNZEO injection dose is not clinically meaningful. The capsules reach their maximum concentration in four to five hours. The drug has a long half-life in the body and an excellent safety record in clinical trials. But it's still unknown whether this drug will work in humans.